Tuesday, March 26, 2024

MTHFR - a debate on Folate and how this is linked to autism plus other health issues

 

I would like to delve into the topic of healing a mutation versus supporting it indefinitely, and whether this is a feasible option.

Did you know that MTHFR is linked to schizophrenia, biopolar disorder, depression, autism, and ADHD?

A small recap of my first blog, we discovered the MTHFR is an enzyme that no longer works properly causing a gene mutation, or so this is what science supports. This mutation led us back to the dna. This also posed the question as to why the enzyme failed to begin with.

In an effort to gather different views on this subject, I reached out to multiple MTHFR Facebook groups, asking if anyone had attempted stem cell therapy to address a mutation. If so, were there any positive or negative outcomes observed. However, I was met with resistance from some of the admin’s, leaving me to ponder why this was not allowed to be asked, despite the prevalence of stem cell therapy in the USA.

A significant challenge in the medical field is the lack of clear and definitive information. Why is there not a straightforward answer regarding which supplement(s) can support this pathway effectively?

One of the most debated supplements in relation to this cycle is folate, and the various forms it can take, such as folic acid, folonic acid, vitamin B9 (folic acid), dihydrofolate (DHF), tetrahydrofolate (THF), 5, 10-methylenetetrahydrofolate (5, 10-MTHF), and 5-methyltetrahydrofolate (5-MTHF).

I came across an interesting article from the CDC (Centers for Disease Control and Prevention) regarding Folic Acid, which states: "You might have read or heard that folic acid is not safe if you have one or two copies of the MTHFR C677T variant. This is not true. Even if you have one or two copies of the MTHFR C677T variant, your body can safely and effectively process all different types of folate, including folic acid." I have posted this link below.

So what does variant mean, "variant" refers to a specific genetic variation or mutation that affects the MTHFR gene. So, having "one or two copies of the MTHFR C677T variant" means having a particular genetic mutation in the MTHFR gene.

I have found myself questioning everything, especially in science and if it is indeed a gene mutation? I came across one doctor who states the MTHFR is just a Riboflavin deficiency; could it possibly be that simple? I have posted Dr. Chris Masterjohn you tube video below.

I have personally tried various forms of folate at the correct dosages that was prescriped from a physcian, including folic acid, with no significant changes observed. It is essential to recognize that other supplements, such as vitamin B's, glutathione (reduced glutathione), and SamE, are also highly recommended for this cycle. Glutathione has become another debated supplement that must be discussed at a later time.

Dr. Richard E Frye's video on Folate Metabolism, Mitochondrial Disease, and Autism discusses scientific studies that have been conducted to determine the absorption percentage of folic acid and its ability to reach the nervous system. Dr. Frye advises against purchasing folic acid over the counter due to additives and inadequate dosages.

I encourage you to watch Dr. Frye's video for valuable insights into folic acid and folate metabolism. I am not endorsing any specific videos or forms of folate. I feel there is much we still are not aware of pertaining to this topic.

Please consult with your own healthcare provider for personalized medical advice. This information is based on my own personal journey.

Numerous studies have found that dysfunction in the MTHFR pathway can lead to elevated homocystein levels, which in turn may contribute to increased risk of brain damage. Professionals have recommended supporting this pathway as a preventive measure against further brain damage. Additionally, research indicates that imbalanced homocystein levels can result in various health issues, highlighting the importance of maintaining proper balance in the body.

This article may contain some thoughts, opionions, research and studies from Autism Granny.

 Your Feedback on your experiences with folate supplementation is welcome and appreciated.  

Please be mindful of other opinions and views, as we all aware that everyone’s body can react differently to supplements.

Make sure and click the follow button for future blogs.

 

https://www.cdc.gov/ncbddd/folicacid/mthfr-gene-and-folic-acid.html

  

https://www.youtube.com/watch?v=ZQ_aFqA5Q_E

Dr. Richard E Frye

 

https://www.youtube.com/watch?v=Fp6u82coOYE

Dr. Chris Masterjohn


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218441/#:~:text=As%20both%20DNA%20methylation%20and,depression%2C%20autism%2C%20and%20ADHD.


 

 


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